Why Vaccines Go Intravascular Every Time
Unpacking the Intravascular Realities of Intramuscular Injections
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After my interview with Dr. Tenpenny last Monday (it should air tomorrow), I responded on X to a statement by Stanford Infectious Disease Professor, Dr Jake Scott, who is now “famous” for being schooled by Senator Ron Johnson on mRNA technology.
What was Dr. Scott’s statement that caught my attention?
Sadly, he erased not only his statement, but his entire X-account immediately after I posted my response…
Dr. Scott contended that intramuscular vaccines stay in the muscle and migrate to the lymph node!
Evidently, it immediately started a storm of comments as the Acuitas distribution study1 had proven that to be wrong long ago. A more recent study of LNP biodistribution2 showed that the draining lymph node, supposedly in the frontline, was not more transfected than other lymph node consolidating that reality.
Interestingly, I had been working on this topic for this article over the weekend, and had drawn a few graphics that I thought would help you all understand better how vaccines and other injectables actually end up going intravascular each time, and why the outcome varies so widely.
I have added these helpful images to the Tweet’s original text for educational purposes, and believe the article is more accessible and effective than the article I had started, so here is my response:
”
Dr. Scott,
Respectfully, you are 100% wrong and utterly uninformed: the vaccine doesn’t stay in the muscle, and not much goes into the lymph node.
It goes directly into the blood stream at random speeds, random concentrations, and random destinations. Effectively, it’s a Russian roulette.
Let me explain why.
It’s unequivocal as it’s basic physics.
When you insert a needle into a muscle, the needle will inevitably severe a multitude of blood vessel mostly capillaries, but also larger veinules and arterioles, and occasionally veins (like the cephalic vein).
When the vaccine fluid is injected into the muscle, it will expand in the interstitial tissue. The Law of pressure gradients dictate that the fluid as it expands, will reach low pressure blood vessels that have been severed, and will be injected directly into the circulatory system.
This will cause a primary bolus of highly concentrated LNPs to go the right heart chambers, then the lungs, the left heart chambers, the aorta and the rest of the body.
By my calculation, this early bolus has an instantaneous concentration 300,000 times higher than the peak concentration obtained after 2 hours when much of the dose is disseminated into the body. A small vessel of 0.1 millimeter distant of 1 mm of the tip of the needle, not an uncommon scenario, produces an instantaneous bolus of 26 million cytotoxic particles, with the theoretical power to destroy 350 sq.cm. of endothelium!
Once this first bolus passed, after a brief pause, another longer bolus will migrate to the holes pushed by the reaction of the muscle fascia to the abnormal pressure caused by the dose. The speed, and therefore the concentration of the secondary bolus intravascularly will be dictated by the largest hole.
Both the Acuitas pharmacokinetic study and similar pharmacokinetic3 studies (notably with epinephrine) show most of the dose goes IV within an hour, mostly in the first 20-30 minutes, as the speed of leakage drops with pressure decrease.
The percentage of the dose staying in the muscle is only dictated by the proportion of interstitial fluid that leaks. If the largest leak is located at the extreme end of the dose expansion, or even further away, indeed a greater portion of the dose will remain in the muscle. But, if the greater hole is close to the tip of the needle, all the dose will go IV.
No matter what, all IM injections have an IV part. So much so that every vaccinated had leaky heart capillaries ( Nakahara et al. / Buergin et al.) even if transiently that’s a very bad sign. One can extrapolate that every vaccinated had leaky capillaries in larger organs like the brain, the ovaries, the gut, the kidneys...
The reality is that the intravascular injection is (delivering) tens of billions of cytotoxic (by proxy) LNPs in a:
- non standardized
- non calibrated
- non route-compliant
- non destination-compliant
way.
Feel free to reach out to me if you want to understand how this flaw in delivery protocl can create thrombosis, thrombocytopenia, calcification, fistulas, aneurysm, white clots, necrosis, leaky blood-tissue barriers, cancers and genetic disorders. #BolusTheory
This is a very fundamental and simple article. Anyone with basic physics understanding can understand what is happening. There is no arcane science. Vaccines were never designed to be administered intravenously, and they are always effectively administered intravascularly.
I hope you found this brief article interesting, and you now have a clearer view as to the inevitability of invisible intravascular injections when injecting in muscles.
With ACIP (Advisory Committee on Immunization Practices) opening up the floor and asking questions about biodistribution, I hope Bolus Theory will get not only more visibility from the media and from investigators, but also a more open and less adversarial mindset.
It’s unfortunate that Dr. Scott refused the debate, because he’s not alone in thinking that delivery is not the problem. Most of the medical world has dismissed the very idea, despite repeated studies on animals validating it.
On the personal front, as I said in my last article, we moved out of Paris. My family is away from me, and I try to support them as much as I can with the bit of money I get from Substack.
I am alone in a remote location in Southern France. As you can see from the material, I am not idle; I am working actively 7 days a week to advance the Bolus Theory, to improve the message, to continue my understanding, and to communicate. Feel free to support my work and my family in any way you can. I had to erase all the links to the Substack paying subscription page, but you can find the link on Substack, or go to Paypal (marc.girardot@icloud.com). I continue to drive forward and help people. Feel free to reach out directly or in the comments.
I hope this time the message won’t go to Spam. Have a lovely Sunday.
Love, Marc
“A Tissue Distribution Study of a [3H]-Labelled Lipid Nanoparticle-mRNA Formulation Containing ALC-0315 and ALC-0159 Following Intramuscular Administration in Wistar Han Rats” - FDA-CBER-2021-5683-0013963
“Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning” by Luo et al. - Reference
“Pharmacokinetic and pharmacodynamic comparison of epinephrine, administered intranasally and intramuscularly:An integrated analysis” by Tanimoto et al.











After 3 years of reading many Substack authors one has to wonder whether most vaccinology is pure fantasy as to its being safe and effective?!?!?! 😢🙏🏻
The third instance still went to spam for me. However, this time when I clicked the "not spam" button it popped up an extra window asking me if I wanted to send it to Google's Spam team for further analysis. I went ahead and sent it to them. Hopefully they aren't biased toward the drug companies and will fix the issue.